Antidiarrhoeal activities of carbazole alkaloids form Murraya koenigii Spreng (Rutaceae) seeds

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DC Field	Value	Language
dc.contributor.author	Nayak, A	-
dc.date.accessioned	2024-09-20T07:06:14Z	-
dc.date.available	2024-09-20T07:06:14Z	-
dc.date.issued	2010	-
dc.identifier.citation	Suvra Mandal, Anupam Nayak, Manoj Kar, Samir K. Banerjee, Ashes Das, S.N. Upadhyay, R.K. Singh, Avijit Banerji and Julie Banerji*. Antidiarrhoeal activities of carbazole alkaloids form Murraya koenigii Spreng (Rutaceae) seeds. Fitoterapia (2010), 81, 72-74.	en_US
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/567	-
dc.description.abstract	The bioassay guided fractionation of the n-hexane extract of the seeds of Murraya koenigii Spreng (Rutaceae) resulted in the isolation of three bioactive carbazole alkaloids, kurryam (I), koenimbine (II) and koenine (III). The structures of the compounds were confirmed from their 1H-, 13C-, and 2D-NMR spectral data. Of the three compounds (I) and (II) exhibited significant inhibitory activity against castor oil-induced diarrhoea and PGE2-induced enteropooling in rats. The compounds also produced a significant reduction in gastrointestinal motility in the charcoal meal test in Wister rats.	en_US
dc.language.iso	en	en_US
dc.publisher	Fitoterapia	en_US
dc.subject	Murraya koenigii	en_US
dc.subject	Carbazole alkaloid	en_US
dc.subject	Seed	en_US
dc.subject	Antidiarrhoeal	en_US
dc.title	Antidiarrhoeal activities of carbazole alkaloids form Murraya koenigii Spreng (Rutaceae) seeds	en_US
dc.type	Article	en_US
Appears in Collections:	Journal Paper / Article

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